I haven't heard much about 250D. I decided to chance it and buy 100' short ends of 250D film and have been bulk loading it.
The colors are fantastic. 'like Portra 400 with Ektar 100's pop!'
I develop it at home in C41 and just use a baking soda prewash to get rid of the ramjet. It doesn't require much of a workflow change, and highly recommend it.